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Early depictions of circa-ninth-century Central Java closely resembled Indic nāga which was determined by imagery of cobras. Throughout this period, nāga-serpents were depicted as huge cobras supporting the waterspout of yoni-lingam.
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b may be the dissociation regular on the group that need to be protonated for total activity. The pH link alternatif naga26 profiles which confirmed which the deprotonation of two acid ic groups as well as the protonation of 1 standard team are essential for optimum activity have been fit to equation five exactly where K
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m while the Zn enzyme has the lowest. Identical trends while in the range of the catalytic constants ended up reported Formerly to the Co, Zn, Mn and Fe reconstitutions of apo-NagA from E. coli
The Nāga (Lao: ພະຍານາກ) is believed to reside in the Laotian stretch on the Mekong or its estuaries. Lao mythology maintains which the nagas will be the protectors of Vientiane, and by extension, the Lao point out. The Affiliation with nagas was most Evidently articulated throughout and right away following the reign of Anouvong.
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Daityas and Dānavas are not capable of recounting his fantastic features. He's honoured by Devas and celestial sages. He's spoken of as Ananta. He has a thousand hoods and He's Evidently bedecked in Svastika ornaments devoid of impurities. He illuminates all quarters by thousand jewels on his hoods.
this residue is hydrogen bonded on the lone drinking water molecule (or hydroxide) that is definitely coordinated to your metallic ion sure to the Mβ-web-site (21). Hence, it is predicted this residue will purpose in catalysis by abstraction of the proton from drinking water before, or concomitant with, the attack of hydroxide around the amide bond from the substrate. Within the detection limits of our assay for item formation, we were struggling to evaluate any catalytic action for either the D273N or D273A mutant.
Residues Q59 and N61 had been mutated alongside one another to some set of histidine residues to make an HxH motif that may be analogous to that present in NagA from B. subtilis